Optimization of self-microemulsifying drug delivery system for phospholipid complex of telmisartan using D-optimal mixture design
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چکیده
منابع مشابه
Development and optimization of a self-microemulsifying drug delivery system for ator vastatin calcium by using d-optimal mixture design
In this study, we developed and optimized a self-microemulsifying drug delivery system (SMEDDS) formulation for improving the dissolution and oral absorption of atorvastatin calcium (ATV), a poorly water-soluble drug. Solubility and emulsification tests were performed to select a suitable combination of oil, surfactant, and cosurfactant. A D-optimal mixture design was used to optimize the conce...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0208339